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1. Seo JP, Trippett JS, Huang Z, Wang R, Lee S, Szablowski JO*, Acoustically-Targeted Measurement of Transgene Expression in the Brain,  bioRxiv 2023.05.23.541868; doi:

2. Nouraein S, Lee S, Saenz VA, Del Mundo HC, Yiu J, Szablowski JO*, Acoustically Targeted Noninvasive Gene Therapy in Large Brain Regions, bioRxiv 2023.01.19.524626, doi: 

3. Lee S, Nouraein S, Kwon JJ, Huang Z, Szablowski JO, Engineered Serum Markers for Noninvasive Monitoring of Gene Expression in the Brain, bioRxiv 2022.07.17.500352; doi:

4. Chen, M., Kim, B., Ruocco, M.1, Fleury, S., Deng, S., Nouraein, S. Lee, S., Butler, S., Szablowski, J.O., Suh, J., Veiseh, O. Systems biology and immune profile characterization of adeno-associated virus identifies B cell-specific targets which enable vector re-administration. Gene Therapy, in press

5. Xia B*, Sebesta C*, Lee S*, Nair V, Zhao X, Coffler S, Robinson JT#, Szablowski JO#, Biohybrid approaches to interface with the nervous system: the best of both worlds, Current Opinion in Biotechnology, 72 (86-94), (2021)

6. Li H, Heath JE, Trippett JS, Shapiro MG#, Szablowski JO#, Engineering viral vectors for acoustically targeted gene delivery. bioRxiv 2021.07.26.453904; doi:


7. Szablowski JO#, Harb M, Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation, JoVE (2020) in press

(# corresponding)

8. Szablowski JO*, Bar-Zion A*, Shapiro MG, Achieving spatial and molecular specificity with ultrasound-targeted biomolecular therapeutics, Accounts of chemical research 52.9 (2019): 2427-2434.

                               * co-first

9. Szablowski JO, Lue B, Lee-Gosselin A, Malounda A, Shapiro MG, Acoustically Targeted Chemogenetics for Noninvasive Control of Neural Circuits, Nature Biomedical Engineering, (2), 475–484 (2018);

[Highlighted in F1000 Prime]

10. Maresca, D, Lakshmanan A, Abedi M, Bar-Zion A, Farhadi A, Lu GJ, Szablowski JO, Wu D, Yoo S, and Shapiro MG, Biomolecular Ultrasound and Sonogenetics. Annual review of chemical and biomolecular engineering, 9:229-252 (2018)

11. Lu, G. J., Farhadi, A., Szablowski, J. O., Lee-Gosselin, A., Barnes, S. R., Lakshmanan, A., ... & Shapiro, M. G. Acoustically modulated magnetic resonance imaging of gas-filled protein nanostructures. Nature Materials 17, 456–463 (2018)

12. Piraner DI, Farhadi A, Davis HC, Wu D, Maresca D, Szablowski JO, Shapiro MG, Going Deeper: Biomolecular Tools for Acoustic and Magnetic Imaging and Control of Cellular Function, Biochemistry 56 (39), 5202-5209 (2018)

13. Mysore VS, Szablowski JO, Dervan PB, Frost PJ, A DNA-binding molecule targeting the adaptive hypoxic response in multiple myeloma has potent in vivo and in vitro anti-tumor effects, Molecular Cancer Research (2016), Mol Cancer Res Published OnlineFirst January 22, 2016 
Featured in highlights: 

14. Szablowski, JO.; Raskatov JA., Dervan, PB. "An HRE-binding Py-Im polyamide attenuates tumor growth and inhibits angiogenesis in vivo."; Molecular Cancer Therapeutics (2015), Mol Cancer Ther molcanther.0719.2015; Published OnlineFirst December 30, 2015
Featured in highlights: 

15. Raskatov JA.; Szablowski, JO.; Dervan, PB.; "Tumor Xenograft Uptake of a Py Im Polyamide Varies as a Function of Cell Line Grafted: a C-14 Study", Journal of Medicinal Chemistry 57 (20), 8471-8476 (2014)

16. Yang, F; Nickols, N; Li, Benjamin; Szablowski, JO; Hamilton, S; Meier, J; Wang, C; Dervan, PB, Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit, Journal of Medicinal Chemistry 56 (18), 7449-7457 (2013)

17. Nickols NG*,Szablowski JO*, Hargrove AE, Li BC, Raskatov JA, Activity of a Py-Im Polyamide Targeted to the Estrogen Response Element, Molecular Cancer Therapeutics, 12:675–84 (2013)

selected as a 'American Association for Cancer Research (AACR) hot topic 2013'.

* co-first

18. Cristina Vilanova, Ángeles Hueso, Carles Palanca, Guillem Marco,Miguel Pitarch, Eduardo Otero, Juny Crespo, Jerzy Szablowski, Sara Rivera,Laura Domínguez-Escribà, Emilio Navarro, Arnau Montagud, Pedro Fernández de Córdoba, Asier González, Joaquín Ariño,Andrés Moya, Javier Urchueguía & Manuel Porcar, "Aequorin-expressing yeast emits light under electric control" , J Biotechnol. 152(3):93-5. (2011)

19. Shapiro MG*, Westmeyer GG*, Romero P, Szablowski JO, Küster B, Shah A, Otey CR, Langer R, Arnold FH, & Jasanoff AP, Directed evolution of an MRI contrast agent for noninvasive imaging of dopamine. Nature Biotechnology 28, 264–270 (2010)

* co-first

20. Shapiro MG, Szablowski JO, Langer R, Jasanoff AP, Protein nanoparticles engineered to sense kinase activity in MRI, Journal of the American Chemical Society 2009 131 (7), 2484-2486


  1. Szablowski JO, Li H, Heath JE, Shapiro MG, Viral Vectors Engineered for Enhanced Ultrasound-Mediated Delivery to the Brain CIT File No.:   CIT-8680-P, Filed: 7/23/2021

  2. Szablowski JO, Shapiro MG, California Institute of Technology, 2019. Methods and systems for noninvasive control of brain cells and related vectors and compositions. U.S. Patent Application 16/213,991.

  3. Lu G, Farhadi A, Szablowski JO, Shapiro MG, Shapiro,Gas-filled structures and related compositions, methods and systems for magnetic resonance imaging., U.S. Patent Application 15/663,600.

  4. Szablowski JO, User-adjustable knee orthosis for patellar instability and related disorders, CIT File 12-216, Provisional Filed: 8/7/2012

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