Laboratory for Noninvasive Neuroengineering

We are developing technologies for noninvasive control and monitoring of the brain. In our work, we combine synthetic biology, molecular engineering, and strategies for enhanced gene and drug delivery into the central nervous system. Our goals are to understand neural circuit function and treat brain disorders with fewer side effects.

Keywords: gene delivery, protein engineering, neuromodulation, viral vector engineering, ultrasound

For examples, see our current research. 














New preprint: Congratulations to Jake Trippett and our team of collaborators at Caltech for developing a viral vector engineered for acoustically-targeted gene delivery.

New Grant: G. Harold and Leila Y. Mathers Charitable Foundation will support our work on Acoustically Targeted Chemogenetics (ATAC).

Congratulations to Manwal Harb, and a lab alum Tsvetelina Baryakova for their NSF GRFP fellowships and to Joycelyn Yiu for the NSF GRFP honorable mention!

New grant: John S. Dunn Foundation will support our work on treating neurodevelopment disorders. Read more


Congratulations to Manwal Harb for being selected for NSF NRT Bioelectronics program.


New paper: a peer-reviewed publication is now in press - a protocol for high-precision FUS-BBBO. Congrats to Manwal Harb for his first co-authorship on a paper.


New grant: We have received a grant from The Welch foundation to develop site-specific therapeutics for brain disorders. 

Invited Talk at Columbia University

Invited talk at Mount Sinai School of Medicine, Neuroscience Center, as a part of #MSNSeminars

ATAC in the news.

Our work on noninvasive neuromodulation was featured in the news. Genetic Engineering & Biotechnology News published an informative article on DREADDs, which also featured ATAC technology.


Noninvasive neuromodulation and Acoustically Targeted Chemogenetics


Gene therapy and gene delivery for the CNS

Site-specific therapeutics

Viral vector and protein engineering

for neuroscience

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6100 Main St., Houston, TX 77005-1892 
Mailing Address: P.O. Box 1892 Houston, TX 77251-1892